Formulation: A solid
Formal Name: N-[(1E)-2-bromo-2-(2-methoxyphenyl)-1-(1-piperidinylcarbonyl)ethenyl]-4-nitro-benzamide
Purity: ≥98%
Formula Markup: C22H22BrN3O5
Formula Weight: 488,3
Shelf life (days): 1460
CAS Number: 211364-06-6
Notes: AT-130 is an antiviral agent.{65209,65210} It is a non-nucleoside inhibitor of hepatitis B virus (HBV) replication in wild-type and rtL180M, rtM204I, and rtL180M + rtL204V lamivudine-resistant strains of HBV (IC50s = 2.4, 1.6, 5.1, and 1.3 µM, respectively).{65210} AT-130 inhibits viral DNA synthesis in HBV-infected HepAD38 cells (EC50 = 0.13 µM) and reduces the amount of encapsidated RNA in HBV-infected HepG2 cells.{65210,65211}