Cephalotaxine, CAS 24316-19-6

Formulation: A solid

Purity: ≥95%

Formula Markup: C18H21NO4

Formula Weight: 315,4

Shelf life (days): 1460

CAS Number: 24316-19-6

Notes: Cephalotaxine is an alkaloid that has been found in Cephalotaxus and has anticancer and antiviral activities.{69041,69042,69043} It is cytotoxic to HL-60, NB4, MOLT-4, K562, Jurkat, and Raji cells (IC50s = 4.91, 16.88, 7.09, 22.59, 5.54, and 18.08 µM, respectively).{69041} Cephalotaxine (5-20 µM) induces mitochondrial apoptosis, as well as impairs lysosomal acidification and autophagic flux in HL-60 cells. It reduces infectivity and hepatitis B virus (HBV) surface antigen (HBsAg) secretion in HBV-infected HepG2 2.2.15 cells when used at concentrations ranging from 10 to 100 µM.{69042} Cephalotaxine (20, 40, and 80 µM) also reduces viral infectivity in Zika virus-infected Vero cells.{69043}

• Artikelnummer: CAY36521-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36521-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK
• Methode: Reinstoffe