CRT0273750, CAS 1979939-16-6

Formulation: A solid

Formal Name: N-[(1S)-1-(4-chlorophenyl)ethyl]-3-[[4-(trifluoromethoxy)phenyl]methyl]-3H-imidazo[4,5-b]pyridine-2-propanamide

Purity: ≥98%

Formula Markup: C25H22ClF3N4O2

Formula Weight: 502,9

Shelf life (days): 1460

CAS Number: 1979939-16-6

Notes: CRT0273750 is an ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2) inhibitor (IC50 = 1 nM).{67249} It prevents lysophosphatidylcholine hydrolysis in a plasma choline release assay (IC50 = 13 nM). CRT0273750 inhibits the migration of 4T1 cells in a migration assay (IC50 = 24 nM). It decreases plasma levels of the ENPP2 hydrolysis product lysophosphatidic acid in an MDA-MB-231 mouse xenograft model.

• Artikelnummer: CAY20904-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 20904-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe