Cytarabine 5′-monophosphate, CAS 7075-11-8

Formulation: A solid

Formal Name: 4-amino-1-(5-O-phosphono-β-D-arabinofuranosyl)-2(1H)-pyrimidinone

Purity: ≥95%

Formula Markup: C9H14N3O8P

Formula Weight: 323,2

Shelf life (days): 1460

CAS Number: 7075-11-8

Notes: Cytarabine 5′-monophosphate (ara-CMP) is an active metabolite of the nucleoside analog cytarabine (Item No. 16069).{62684} It is formed from cytarabine by deoxycytidine kinase.{48672} ara-CMP is incorporated into DNA by DNA polymerase α, which slows the rate of DNA synthesis by approximately 2,000-fold in a cell-free assay.{62685} It inhibits nuclear and mitochondrial DNA replication in S. cerevisiae when used at a concentration of 15 mM.{62686} ara-CMP (3.5-75.1 mg/kg) improves survival in an L1210 murine leukemia model.{62687}

• Artikelnummer: CAY36496-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36496-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe