Dictamnine, CAS 484-29-7

Formulation: A solid

Formal Name: 4-methoxy-furo[2,3-b]quinoline

Purity: ≥95%

Formula Markup: C12H9NO2

Formula Weight: 199,2

Shelf life (days): 1460

CAS Number: 484-29-7

Notes: Dictamnine is an alkaloid that has been found in D. dasycarpus and has diverse biological activities.{58901,58902,58903} It inhibits platelet aggregation induced by arachidonic acid (Item Nos. 90010 / 90010.1 / 10006607), collagen, thrombin, or platelet-activating factor (PAF) in washed isolated rabbit platelets when used at a concentration of 100 µg/ml.{58902} Dictamnine is cytotoxic to human KB oral, HeLa cervical, and DLD-1 colon cancer cells (EC50s = 20.55, 2.5, and 6.4 µg/ml, respectively) and induces apoptosis in A549, PC-9, and EBC-1 human lung cancer cells when used at concentrations ranging from 50 to 200 µM.{58902,58901} It increases serum alanine aminotransferase (ALT) and alkaline phosphatase (ALP) activities and induces hepatocyte necrosis in mice when administered at doses of 150 or 200 mg/kg.{58903}

• Artikelnummer: CAY34646-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34646-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe