Forphenicinol, CAS 71522-58-2

Formulation: A solid

Formal Name: αS-amino-3-hydroxy-4-(hydroxymethyl)-benzeneacetic acid

Purity: ≥90%

Formula Markup: C9H11NO4

Formula Weight: 197,2

Shelf life (days): 1460

CAS Number: 71522-58-2

Notes: Forphenicinol is an immunomodulator and a derivative of the bacterial metabolite forphenicine (Item No. 33504).{68126} It increases the phagocytosis of yeast by peritoneal macrophages isolated from thioglycolate-stimulated mice. Forphenicinol (100 µg/animal) prevents cyclophosphamide-induced suppression of delayed-type hypersensitivity (DTH), as well as enhances DTH in response to the hapten oxazolone or sheep red blood cells in mice. It enhances the bactericidal activity of macrophages against P. aeruginosa in mice when administered at a dose of 0.5 mg/kg.{68128} Forphenicinol (15.6-1,000 µg/animal) increases survival in a mouse model of P. aeruginosa infection.{68127} It also inhibits tumor growth in S180 sarcoma and IMC carcinoma mouse xenograft models when administered at doses ranging from 0.05 to 5 mg/kg per day.

• Artikelnummer: CAY36382-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36382-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe