Formulation: A solid
Formal Name: L-γ-glutamyl-L-phenylalanine, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C14H18N2O5 • XCF3COOH
Formula Weight: 294,3
Shelf life (days): 1460
Notes: γ-Glu-Phe is an endogenous dipeptide that is composed of L-glutamic acid (Item No. 30377) and L-phenylalanine (Item No. 31498) and has also been found in Allium.{65376} It prevents increases in lipid accumulation in AML12 hepatocytes stimulated with oleic acid (Item Nos. 90260 / 24659) when used at a concentration of 30 µM. γ-Glu-Phe (2.5-10 mM) increases levels of the calcium-sensing receptor (CaSR) and secretion of cholecystokinin (CCK) and glucagon-like peptide 1 (GLP-1) in STC-1 enteroendocrine cells.{65377} Changes in urine levels of γ-Glu-Phe are associated with hypertension and phenylketonuria (PKU) and changes in serum levels are associated with prostate cancer.{65378,65380,65379}