Gap 26 (trifluoroacetate salt), CAS 197250-15-0

Formulation: A solid

Formal Name: L-valyl-L-cysteinyl-L-tyrosyl-L-α-aspartyl-L-lysyl-L-seryl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-seryl-L-histidyl-L-valyl-L-arginine, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C70H107N19O19S • XCF3COOH

Formula Weight: 1550,8

Shelf life (days): 1460

CAS Number: 197250-15-0

Notes: Gap 26 is a connexin-mimetic peptide that corresponds to amino acids 63-75 of extracellular loop 1 in connexin 43.{67015} It inhibits phenylephrine-induced rhythmic contractile activity in isolated rabbit superior mesenteric arterial strips (IC50 = 28.4 µM). Gap 26 (0.25 mg/ml) inhibits photoliberated Ins(1,4,5)-P3-induced ATP release in ECV304 cells.{67016} It decreases the infarct size in a rat model of myocardial infarction induced by left coronary artery occlusion when administered at doses of 0.5, 1, and 10 µg/kg.{67017}

• Artikelnummer: CAY36625-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36625-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe