Formulation: A solid
Formal Name: 3-ethyl-4-hydroxy-6-(1-methylethyl)-2H-pyran-2-one
Purity: ≥95%
Formula Markup: C10H14O3
Formula Weight: 182,2
Shelf life (days): 1460
CAS Number: 150973-78-7
Notes: Germicidin B is a pyranone antibiotic originally derived from Streptomyces. It acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM.{31633,31632} During germination, spores of Streptomyces excrete germicidin B along with other germicidin homologs, which inhibit germination of its own arthrospores.{31633,31632} At higher concentrations, germicidin can inhibit the porcine brain Na+/K+-dependent ATPase (ID50 = 100 µM) and prevent the germination of the cress L. sativum.{31633}