Homocitrulline, CAS 1190-49-4

Formulation: A solid

Formal Name: N6-(aminocarbonyl)-L-lysine

Purity: ≥95%

Formula Markup: C7H15N3O3

Formula Weight: 189,2

Shelf life (days): 1460

CAS Number: 1190-49-4

Notes: Homocitrulline is an amino acid and a product of carbamylation, a post-translational modification of proteins and amino acids.{34536,34533} It is formed by the adduction of isocyanic acid, a product of urea degradation or thiocyanate oxidation induced by myeloperoxidase (MPO), to the ε-amino group of lysine residues.{34533} Protein-bound homocitrulline levels are increased in the aortas of transgenic Ldlr-/- mice expressing human MPO fed a high-fat atherogenic diet.{32815} Intra-articular injection of homocitrulline-containing peptides induce the development of arthritis in mice.{32805} Homocitrulline-containing peptide and anti-homocitrulline antibody levels are increased in whole blood from patients with erosive rheumatoid arthritis compared to patients with non-erosive rheumatoid arthritis.

• Artikelnummer: CAY34980-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34980-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK
• Methode: Reinstoffe