Homocitrulline-d3

Homocitrulline-d3
Artikelnummer
CAY36339-1
Verpackungseinheit
1 mg
Hersteller
Cayman Chemical

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Formulation: A solid

Formal Name: N6-carbamoyl-L-lysine-2,6,6-d3

Purity: ≥99% deuterated forms (d1-d3)

Formula Markup: C7H12D3N3O3

Formula Weight: 192,2

Shelf life (days): 1460

Notes: Homocitrulline-d3 is intended for use as an internal standard for the quantification of homocitrulline (Item No. 34980) by GC- or LC-MS. Homocitrulline is an amino acid and a product of carbamylation, a post-translational modification of proteins and amino acids.{34536,34533} It is formed by the adduction of isocyanic acid, a product of urea degradation or thiocyanate oxidation induced by myeloperoxidase (MPO), to the ε-amino group of lysine residues.{34533} Protein-bound homocitrulline levels are increased in the aortas of transgenic Ldlr-/- mice expressing human MPO fed a high-fat atherogenic diet.{32815} Intra-articular injection of homocitrulline-containing peptides induces the development of arthritis in mice.{32805} Homocitrulline-containing peptide and anti-homocitrulline antibody levels are increased in whole blood from patients with erosive rheumatoid arthritis compared to patients with non-erosive rheumatoid arthritis.
Mehr Informationen
Artikelnummer CAY36339-1
Hersteller Cayman Chemical
Hersteller Artikelnummer 36339-1
Green Labware Nein
Verpackungseinheit 1 mg
Mengeneinheit STK
Methode GC-MS, LC-MS, Isotopenmarkierung
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