Formulation: A solid
Formal Name: 5,6-dihydro-5-oxo-indolo[1,2-a]quinazoline-7-acetic acid
Purity: ≥90%
Formula Markup: C17H12N2O3
Formula Weight: 292,3
Shelf life (days): 1460
CAS Number: 391670-48-7
Notes: IQA is a casein kinase 2 (CK2) inhibitor (IC50 = 0.39 µM).{21491} IQA is selective for CK2 over protein kinase A (PKA), glycogen synthase kinase 3β (GSK3β), lymphocyte cell-specific protein tyrosine kinase (LCK), dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), and PI3Kγ (IC50s = 16, 14, 11, 8, and >200 µM, respectively). IQA decreases the viability of Jurkat leukemia cells in a concentration-dependent manner.{67107}