Isomeranzin, CAS 1088-17-1

Formulation: A solid

Formal Name: 7-methoxy-8-(3-methyl-2-oxobutyl)-2H-1-benzopyran-2-one

Purity: ≥98%

Formula Markup: C15H16O4

Formula Weight: 260,3

Shelf life (days): 1460

CAS Number: 1088-17-1

Notes: Isomeranzin is a coumarin that has been found in C. grandis and has antioxidant and anti-inflammatory activities.{66080,66081} It inhibits superoxide anion generation in, and elastase release from, isolated human neutrophils stimulated with cytochalasin B (Item No. 11328) and fMLP (IC50s = 3.89 and 4.33 µM, respectively).{66080} Isomeranzin (30 µM) inhibits LPS-induced nitric oxide (NO) release in RAW 264.7 macrophages.{66081} It improves survival in a mouse model of LPS-induced septic shock and decreases disease severity in a mouse model of colitis induced by dextran sulfate (DSS; Item No. 23250) when administered at a dose of 30 mg/kg.

• Artikelnummer: CAY35827-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35827-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe