Formulation: A solid
Formal Name: N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-glutamic acid, disodium salt
Formula Markup: C20H21N7O7 • 2Na
Formula Weight: 517,4
Shelf life (days): 1460
CAS Number: 914800-65-0
Notes: 10-Formyltetrahydrofolate is a formyl donor and cofactor, as well as a metabolite of 5,10-methylenetetrahydrofolic acid (folitixorin; Item No. 33967).{65260} It is formed from 5,10-methylenetetrahydrofolic acid by methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) in the cytosol and MTHFD2 and MTHFD2L in the mitochondria. 10-Formyltetrahydrofolate provides the formyl group for conjugation to methionine-tRNA, which is required for mitochondrial protein translation initiation, and is also involved in purine biosynthesis.{65261,48688}