Formulation: A solid
Formal Name: (3α,5β,20S)-3,17,20,21-tetrahydroxy-pregnan-11-one
Purity: ≥98%
Formula Markup: C21H34O5
Formula Weight: 366,5
Shelf life (days): 1460
CAS Number: 516-42-7
Notes: α-Cortolone is a metabolite of the glucocorticoid cortisol (hydrocortisone; Item No. 20739).{64470} It is formed from cortisol by 20α-hydroxysteroid dehydrogenase (20α-HSD) via a tetrahydrocortisone (THE; Item No. 34344) intermediate. Urinary levels of α-cortolone are decreased in patients with severe anorexia nervosa and in postmenopausal women with endometrial adenocarcinoma compared to postmenopausal women without endometrial adenocarcinoma.{64471,64472}