Notes: (–)-β-Sesquiphellandrene is a sesquiterpene that has been found in Z. officinale and has antiviral and anticancer activities.{62597,62578} It reduces rhinovirus IB virus replication in a plaque reduction assay (IC50 = 0.44 µM).{62597} (–)-β-Sesquiphellandrene is cytotoxic to HCT116 cells when used at a concentration of 10 µM.{62578}