C-87, CAS 332420-90-3

Formulation: A solid

Formal Name: 4-[2-(4-chloro-3-nitrophenyl)hydrazone]3-phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione

Purity: ≥95%

Formula Markup: C24H15ClN6O3S

Formula Weight: 502,9

Shelf life (days): 1460

CAS Number: 332420-90-3

Notes: C-87 is an inhibitor of TNF-α.{69330} It binds to TNF-α and reduces the levels of phosphorylated JNK, prevents TNF-α-induced IκBα degradation, and inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 µM) in L-929 cells. It reduces liver inflammation and injury, as well as increases survival, in a mouse model of acute hepatitis induced by LPS and galactosamine (GalN) when administered at a dose of 12.5 mg/kg.

• Artikelnummer: CAY36578-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36578-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe