Formal Name: D-asparaginyl-D-tyrosyl-D-seryl-D-lysyl-D-prolyl-D-threonyl-D-α-aspartyl-D-arginyl-D-glutaminyl-D-tyrosyl-D-histidyl-D-phenylalanine, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C70H98N20O21 • XCF3COOH
Formula Weight: 1555,7
Shelf life (days): 1460
Notes: (D)-PPA 1 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1).{68073} It binds to the extracellular domain of PD-L1 (Kd = 0.51 µM for the recombinant human protein). (D)-PPA 1 (2 mg/kg) decreases tumor volume and improves survival in a CT26 murine colorectal cancer model.