Histone H4 (human, recombinant; His-tagged)

Formulation: A solution in water

Purity: ≥80% estimated by SDS-PAGE

Shelf life (days): 180

Notes: Histone H4 is one of four core histone proteins that are involved in the organization of DNA into chromatin.{18136} Histones are globular proteins with unstructured N-terminal tails and are subject to a variety of post-translational modifications (PTMs), such as methylation, acetylation, phosphorylation, and citrullination, that can influence chromatin structure and regulate gene transcription.{18136,57056} Histone H4 PTMs function as epigenetic regulators of transcription by affecting chromatin structure and enhancing transcription factor binding, as well as play a key role in the maintenance of genomic integrity.{59518,59517} Levels of histone H4 are increased in the inferior and middle temporal gyrus in postmortem brains from patients with Alzheimer’s disease.{59519}

• Artikelnummer: CAY38257
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38257-250
• Green Labware: Nein
• Verpackungseinheit: 250 µg
• Mengeneinheit: STK
• Methode: Western Blotting, Reinstoffe