HIV-1 Integrase Inhibitor 1, CAS 729607-74-3

Formulation: A solid

Formal Name: N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-4-pyrimidinecarboxamide

Purity: ≥98%

Formula Markup: C17H19FN4O5S

Formula Weight: 410,4

Shelf life (days): 1460

CAS Number: 729607-74-3

Notes: HIV-1 integrase inhibitor 1 is an inhibitor of HIV-1 integrase DNA strand transfer (IC50 = 14 nM).{66419} It is also an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), when used at a concentration of 10 µM in a fluorescence-based assay.{66420} HIV-1 integrase inhibitor 1 decreases SARS-CoV-2 replication (EC50 = 0.27 µM) and reduces particle-forming units (PFUs) in infected Huh7.5 cells in a concentration-dependent manner.

• Artikelnummer: CAY36807-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36807-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK
• Methode: Reinstoffe