Formulation: A solid
Formal Name: 2S-piperidinecarboxylic acid
Purity: ≥95%
Formula Markup: C6H11NO2
Formula Weight: 129,2
Shelf life (days): 1460
CAS Number: 3105-95-1
Notes: L-Pipecolic acid is a metabolite of the amino acid L-lysine.{68255} L-Pipecolic acid is oxidized to L-α-aminoadipic acid by α-aminoadipic semialdehyde dehydrogenase (α-AASA dehydrogenase) and peroxisomal sarcosine oxidase (PSO).{68258,68259} L-Pipecolic acid inhibits GABA binding in bovine brain homogenate in the presence, but not absence, of hexobarbital or pentobarbital (IC50s = 0.2 and 2 nM, respectively).{68256} Serum levels of L-pipecolic acid are elevated in patients with Zellwager syndrome, a peroxisomal condition characterized by hepatomegaly, abnormal facial features, and cognitive impairments.{68257}