Formulation: A lyophilized powder
Formal Name: (3S,6S,9S,12S,18S,21S)-18-((1H-indol-3-yl)methyl)-6-(3-amino-3-oxopropyl)-21-carbamoyl-12-(carboxymethyl)-25-((2,4-dinitrophenyl)amino)-3-((S)-2-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetamido)-3-methylbutanamido)-9-(2-(methylthio)ethyl)-4,7,10,13,16,19-hexaoxo-5,8,11,14,17,20-hexaazapentacosanoic acid, ammonium salt
Purity: ≥95%
Formula Markup: C60H74N14O21S • XNH3
Formula Weight: 1359,4
Shelf life (days): 1460
Notes: Mca-VDQMDGW-K(Dnp)-NH2 is a substrate for caspase-3.{36444} Upon cleavage by caspase-3, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify caspase-3 activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.