ODM-207, CAS 1801503-93-4

Formulation: A solid

Formal Name: 6-(3,5-dimethyl-4-isoxazolyl)-7-methoxy-3-methyl-1-(2-pyridinylmethyl)-2(1H)-quinolinone

Purity: ≥98%

Formula Markup: C22H21N3O3

Formula Weight: 375,4

Shelf life (days): 1460

CAS Number: 1801503-93-4

Notes: ODM-207 is an inhibitor of bromodomain and extra terminal domain (BET) bromodomains. It reduces the proliferation of isolated human metastatic apocrine sweat gland cancer cells (IC50 = 1.99 µM).{64925} ODM-207, in combination with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib (Item No. 10621), decreases proliferation of, and induces DNA double-strand breaks in, isolated human metastatic apocrine sweat gland cancer cells deficient in partner and localizer of BRCA2 (PALB2; IC50 = 650 nM).

• Artikelnummer: CAY37757-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37757-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe