Formulation: A crystalline solid
Formal Name: (E)-6-(2-(3-(dicyanomethylene)-5,5-dimethylcyclohex-1-en-1-yl)vinyl)naphthalen-2-yl 2-fluoro-5-nitrobenzoate
Purity: ≥98%
Formula Markup: C30H22FN3O4
Formula Weight: 507,5
Shelf life (days): 730
Notes: PSP is a two-photon fluorescent probe for hydrogen polysulfide (H2Sn), a reactive sulfur species (RSS) formed during ferroptosis.{57973} Upon reaction with H2Sn, the 2-fluoro-5-nitro-benzoate quenching group of PSP is removed, resulting in the release of a near-infrared emitting product. PSP is selective for H2Sn over a panel of reactive oxygen species (ROS), reactive nitrogen species (RNS), metal ions, and sulfur-containing ions. It has been used to detect H2Sn in live cells and tumor spheroids in vitro.