rac-Benpyrine, CAS 1333714-43-4

Formulation: A solid

Formal Name: 1-(phenylmethyl)-4-(9H-purin-6-ylamino)-2-pyrrolidinone

Purity: ≥98%

Formula Markup: C16H16N6O

Formula Weight: 308,3

Shelf life (days): 1460

CAS Number: 1333714-43-4

Notes: rac-Benpyrine is an inhibitor of the protein-protein interaction between TNF-α and TNF receptor 1 (TNFR1; IC50 = 0.109 µM).{65245} It reduces TNF-α-induced cytotoxicity in L-929 fibroblasts when used at a concentration of 10 µM, as well as prevents nuclear translocation of NF-κB in RAW 264.7 macrophages. rac-Benpyrine (25 mg/kg) improves survival in a mouse model of LPS-induced endotoxemia and decreases disease severity in mouse models of collagen-induced arthritis and imiquimod-induced psoriasis.

• Artikelnummer: CAY36680-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36680-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe