Sermorelin (acetate), CAS 516482-86-3

Formulation: A solid

Formal Name: 29-L-argininamide-1-29-somatoliberin (human pancreatic islet), acetate

Purity: ≥95%

Formula Markup: C149H246N44O42S • XC2H4O2

Formula Weight: 3357,9

Shelf life (days): 1460

CAS Number: 516482-86-3

Notes: Sermorelin is a 29-residue N-terminal analog of growth hormone-releasing hormone (GHRH) that retains the ability to stimulate growth hormone (GH) release.{36354} Sermorelin (1 μg/kg, i.v.) increases serum GH levels in rats by approximately 17% compared with saline control after 15 minutes.{36356} It also increases GH release in pigs when administered at a dose of 250 ng/kg.{36355} Sermorelin (1 μM) increases proliferation of NCI-H727 human bronchial carcinoid cells by 30% and increases vascular endothelial growth factor (VEGF) secretion.{36357} It increases phosphorylation of focal adhesion kinase (FAK) and expression of VEGF in A549 lung cancer cells when used at a concentration of 0.1 μM.{36358} Formulations containing sermorelin have been used to diagnose and treat growth hormone deficiency.

• Artikelnummer: CAY36696-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36696-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: Reinstoffe