Formulation: A solid
Formal Name: (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl-5-d)-2-cyano-5-((isobutyryloxy)methyl)tetrahydrofuran-3,4-diyl, bis(2-methylpropanoate)
Purity: ≥95%
Formula Markup: C24H30DN5O7
Formula Weight: 502,5
Shelf life (days): 1460
CAS Number: 2647442-33-7
Notes: VV116 is an antiviral agent and a derivative of the antiviral prodrug remdesivir (Item No. 30354).{68205} It inhibits viral replication of respiratory syncytial virus (RSV) in A549 cells (EC50 = 1.01 µM). VV116 (25 mg/kg) decreases viral replication and lung viral titer counts in a mouse model of RSV infection. It also decreases alveolar inflammation in RSV-infected mice.