Formulation: A solid
Formal Name: α-phenyl-α-propoxy-benzeneacetic acid, 1-methyl-4-piperidinyl ester, monohydrochloride
Purity: ≥98%
Formula Markup: C23H29NO3 • HCl
Formula Weight: 403,9
Shelf life (days): 1460
CAS Number: 54556-98-8
Notes: Propiverine is an antagonist of muscarinic acetylcholine receptors (mAChRs).{65340} It binds to M1 and M2 mAChRs in rat bladder and submaxillary gland, respectively (Kis = 0.3 and 0.19 µM, respectively), and inhibits carbachol-induced contraction of bladder strips isolated from patients with normal bladder activity and detrusor overactivity associated with benign prostatic hyperplasia (pA2s = 7.7 and 7.6, respectively).{65341} Formulations containing propiverine have been used in the treatment of overactive bladder.