PTIQ, CAS 1032822-42-6

Formulation: A solid

Formal Name: 1-(3,4-dihydro-7-hydroxy-6-methoxy-2(1H)-isoquinolinyl)-1-propanone

Purity: ≥95%

Formula Markup: C13H17NO3

Formula Weight: 235,3

Shelf life (days): 1460

CAS Number: 1032822-42-6

Notes: PTIQ is a neuroprotective compound.{60561} It inhibits tetrahydro-L-biopterin-induced cytotoxicity and increases in matrix metalloproteinase-3 (MMP-3) levels in CATH.a cells (IC50s = 1.8 and 0.06 µM, respectively). PTIQ inhibits LPS-induced production of MMP-3, TNF-α, and COX-2 in BV-2 microglia (IC50s = 2.4, 6.5, and 9.3 µM, respectively). In vivo, PTIQ (3 and 30 mg/kg) increases survival of striatal nigral dopaminergic neurons, reduces microglial activation, and alleviates motor deficits in a mouse model of MPTP-induced Parkinson’s disease.

• Artikelnummer: CAY33540-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33540-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK
• Methode: Reinstoffe