XMD8-87, CAS 1234480-46-6

Formulation: A crystalline solid

Formal Name: 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

Purity: ≥98%

Formula Markup: C24H27N7O2

Formula Weight: 445,5

Shelf life (days): 1460

CAS Number: 1234480-46-6

Notes: XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC50 value of 1.9 μM in HEK293T cells expressing human TNK2.{37179} It is selective for TNK2 over a panel of approximately 100 kinases with >90 and 50s = 0.1-77 nM) commonly found in leukemias but has no effect on cells expressing wild-type TNK2 (IC50 = >1 μM).

• Artikelnummer: CAY23354-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23354-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe