Formulation: A solid
Formal Name: N,N,N-trimethyl-2,3-bis[(1-oxohexadecyl)oxy]-1-propanaminium, monochloride
Purity: ≥95%
Formula Markup: C38H76NO4 • Cl
Formula Weight: 646,5
Shelf life (days): 1460
CAS Number: 139984-36-4
Notes: DPTAP is a cationic lipid that has been used as a transfection reagent in vitro and in vivo and in the formation of liposomes and microbubbles.{69433,69434,69435} Microbubbles containing DPTAP and encapsulating the microRNA (miRNA) miR-145 reduce atherosclerotic plaque area by 48.04% using ultrasound-targeted microbubble destruction (UTMD) in ApoE-/- mice in a model of atherosclerosis induced by a high-fat diet.{69435}