113-O12B, CAS 2803699-72-9

Formulation: A solution in methyl acetate

Formal Name: tetrakis(2-(octyldisulfaneyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(ethane-2,1-diyl))bis(azanetriyl))tetrapropionate

Purity: ≥98%

Formula Markup: C57H111N3O8S8

Formula Weight: 1223

Shelf life (days): 730

CAS Number: 2803699-72-9

Notes: 113-O12B is a disulfide bond-containing ionizable cationic lipidoid.{65448} It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. Subcutaneous administration of LNPs containing 113-O12B and encapsulating an mRNA reporter accumulate specifically in mouse lymph nodes. LNPs containing 113-O12B and encapsulating mRNA encoding ovalbumin reduce tumor growth and increase the number of tumoral CD8+ T cells, M1-like macrophages, and activated dendritic cells in an ovalbumin-expressing B16/F10 murine melanoma model.

• Artikelnummer: CAY37671-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37671-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe