80-O16B, CAS 1624618-02-5

Formulation: A solution in ethanol

Formal Name: N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-β-alanine, 2-(dodecyldithio)ethyl ester

Purity: ≥98%

Formula Markup: C39H78N2O4S4

Formula Weight: 767,3

Shelf life (days): 365

CAS Number: 1624618-02-5

Notes: 80-O16B is a disulfide bond-containing ionizable cationic lipidoid.{64680} It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 for genome editing in mice. LNPs containing 80-O16B conjugated to phenylboronic acid (PBA) and encapsulating an mRNA reporter increase luciferase reporter expression in HeLa cancer cells.{64681} LNPs containing 80-O16B conjugated to PBA and encapsulating p53 mRNA decrease the viability of DU145 prostate and SiHa and HeLa cervical cancer cells.

• Artikelnummer: CAY37564-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37564-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe