Notes: 93-O17S is a chalcogen-containing ionizable cationic lipidoid.{60618} It has been used in the synthesis of lipid nanoparticles (LNPs) for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice. LNPs containing 93-O17S have been used for the intratumoral delivery of cGAMP to enhance cross-presentation of tumor antigens and stimulation of interferon genes (STING) activation in a B16/F10 murine melanoma model.{60481}