Cho-Arg (trifluoroacetate salt), CAS 1609010-56-1

Formulation: A solution in ethanol

Formal Name: cholest-5-en-3-ol (3β)-3-[6-[[(2S)-2-amino-5-[(aminoiminomethyl)amino]-1-oxopentyl]amino]hexanoate], 2,2,2-trifluoroacetate (1:2)

Purity: ≥95%

Formula Markup: C39H71N5O3 • 2CF3COO

Formula Weight: 884,1

Shelf life (days): 365

CAS Number: 1609010-56-1

Notes: Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group.{44005} It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167). It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml).

• Artikelnummer: CAY25943-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25943-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK