DMHAPC-Chol, CAS 794494-38-5

Formulation: A crystalline solid

Formal Name: (3β)-cholest-5-en-3-ol 3-[N-[3-[(2-hydroxyethyl)dimethylammonio]propyl]carbamate]

Purity: ≥95%

Formula Markup: C35H63N2O3

Formula Weight: 559,9

Shelf life (days): 730

CAS Number: 794494-38-5

Notes: DMHAPC-Chol is a cationic cholesterol.{47185} Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells when used at lipid concentrations greater than 20 µM. DMHAPC-Chol, as part of a lipoplex with DOPE (Item No. 15091), has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF.{47186,47187}

• Artikelnummer: CAY26582-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26582-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK