Formulation: A solution in ethanol
Formal Name: N-[(25Z)-14-[(9Z)-9-octadecen-1-yloxy]-3,6,9,12,16-pentaoxatetratriacont-25-en-1-yl]-1H-imidazole-5-carboxamide
Purity: ≥95%
Formula Markup: C51H95N3O7
Formula Weight: 862,3
Shelf life (days): 365
CAS Number: 2758097-38-8
Notes: DOG-IM4 is an ionizable cationic lipid (apparent pKa = 5.6) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA.{67333} Immunization with LNPs containing DOG-IM4 and encapsulating mRNA encoding influenza A hemagglutinin (HA) increases HA-inhibiting antibody titers (HI titers) in mice and cynomolgus macaques.