DSPE-PEG(2000)-NHS

Formulation: A solid

Formal Name: (2R)-3-((((14-((2,5-dioxopyrrolidin-1-yl)oxy)-4,14-dioxo-5,8,11-trioxa-3-azatetradecyl)oxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl distearate

Purity: ≥90%

Formula Markup: (C2H4O)nC51H93N2O15P

Shelf life (days): 1460

Notes: DSPE-PEG(2000)-NHS is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE; Item No. 15095).{69141} It has been used in the generation of micelles and in combination with other lipids in the formation of liposomes. DSPE-PEG(2000)-NHS-containing liposomes localize to the liver and tumor after intravenous administration in mice. Liposomes containing DSPE-PEG(2000)-NHS conjugated to the breast cancer targeting H6 peptide and encapsulating the DNA topoisomerase inhibitor doxorubicin (Item No. 15007) reduce tumor growth in an SK-BR-3 breast cancer mouse xenograft model.

• Artikelnummer: CAY37275-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37275-250
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK
• Methode: Reinstoffe