C12-200, CAS 1220890-25-4

Formulation: A solution in ethanol

Formal Name: 1,1′-[[2-[4-[2-[[2-[bis(2-hydroxydodecyl)amino]ethyl](2-hydroxydodecyl)amino]ethyl]-1-piperazinyl]ethyl]imino]bis-2-dodecanol

Purity: ≥95%

Formula Markup: C70H145N5O5

Formula Weight: 1136,9

Shelf life (days): 730

CAS Number: 1220890-25-4

Notes: C12-200 is a branched-chain ionizable cationic lipidoid.{69044,69045} It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA, siRNA, or self-amplifying RNA (saRNA). LNPs containing C12-200 and encapsulating an mRNA reporter selectively accumulate in the liver, and to a lesser extent in the spleen and pancreas, in mice.{69044} Administration of human erythropoietin (EPO) mRNA or factor VII siRNA in C12-200-containing LNPs increases serum EPO levels and reduces factor VII serum levels, respectively, in mice.

• Artikelnummer: CAY36699-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36699-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK