Formulation: A solution in ethanol
Formal Name: dioctyl 3,3'-((8-((1-((2-(1H-imidazol-1-yl)ethyl)amino)-1-oxo-4-((3-oxo-3-(tridecyloxy)propyl)thio)butan-2-yl)amino)-8-oxooctane-1,3-diyl)bis(sulfanediyl))dipropionate
Purity: ≥95%
Formula Markup: C55H100N4O8S3
Formula Weight: 1041,6
Shelf life (days): 730
Notes: Lipid CP-LC-1447 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid. This lipid has demonstrated an efficient delivery and high protein expression of different kinds of RNA (mRNA, cRNA and saRNA) in vivo. Moreover, using a typical LNP formulation (IL/Ch/DOPE/PEG: 50/38.5/10/1.5), it has shown to induce specific spleen targeting much more efficiently that other commercial alternatives through IV injection, with no signs of toxicity.