DC-Chol (hydrochloride), CAS 166023-21-8

Formulation: A crystalline solid

Formal Name: (3β)-cholest-5-en-3-ol 3-[N-[2-(dimethylamino)ethyl]carbamate], monohydrochloride

Purity: ≥95%

Formula Markup: C32H56N2O2 • HCl

Formula Weight: 537,3

Shelf life (days): 730

CAS Number: 166023-21-8

Notes: DC-Chol is a cationic cholesterol derivative.{47233} DC-Chol, as a component of lipoplexes with 1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE; Item No. 15091), has been used for transfection of mRNA into A549 cells without affecting cell viability. Incubation of DC-chol/1,2-DOPE liposomes or lipoplexes with human whole blood has no effect on neutrophil elastase or β-thromboglobulin levels or the number of platelets and red and white blood cells, indicating hemocompatibility. DC-Chol has also been widely used in the synthesis of liposomes for the delivery of siRNA, DNA, and chemotherapeutic agents into cells and mice.{47234,47235,47236,47237}

• Artikelnummer: CAY16943-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16943-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK