IC8, CAS 2349307-32-8

Formulation: A solid

Formal Name: 1,1',1'',1'''-((piperazine-1,4-diylbis(propane-3,1-diyl))bis(azanetriyl))tetrakis(tetradecan-2-ol)

Purity: ≥95%

Formula Markup: C66H136N4O4

Formula Weight: 1049,8

Shelf life (days): 730

CAS Number: 2349307-32-8

Notes: IC8 is an ionizable cationic lipid.{68234,68235} It has been used in combination with other lipids for the formation of lipid nanoparticles (LNPs). Immunization with severe acute respiratory coronavirus 2 (SARS-CoV-2) spike glycoprotein mRNA in IC8- and manganese-containing LNPs induces IgG responses to SARS-CoV-2 Delta and Omicron variants in mice.{68234} Administration of mRNA encoding B7-H3 X CD3 bispecific T cell engaging (BiTE) antibodies in IC8-containing LNPs reduces tumor growth in MV4-11 and A375 mouse xenograft models.{68235}

• Artikelnummer: CAY37986-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37986-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe