Lipid Catechol

Formulation: A solid

Formal Name: ditetradecyl (((2-(diethylamino)ethyl)amino)(3,4-dihydroxyphenyl)methyl)phosphonate

Purity: ≥95%

Formula Markup: C41H79N2O5P

Formula Weight: 711,1

Shelf life (days): 730

Notes: Lipid catechol is a lipid that contains an α-aminophosphonate group, two 14-carbon acyl chains, and a catechol ring that forms a covalent bond with boronic acid-containing compounds to form lipid prodrug nanoassemblies (LPNA).{65748} LPNAs composed of lipid catechol conjugated to phenylboronic acid-modified ciprofloxacin (CIP-PBA) inhibit the formation of, and disrupt preformed, S. aureus biofilms and eradicate staphylococci in a mouse model of peritoneal S. aureus infection. LPNAs composed of lipid catechol conjugated to bortezomib (BTZ) reduce tumor growth and increase survival in a 4T1 murine mammary carcinoma model.

• Artikelnummer: CAY38665-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38665-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK