L202, CAS 2170488-92-1

Formulation: A solution in ethanol

Formal Name: 1-methyl-4-piperidinecarboxylic acid, 2-[9-oxo-9-[(3-pentyloctyl)oxy]nonyl]dodecyl ester

Purity: ≥95%

Formula Markup: C41H79NO4

Formula Weight: 650,1

Shelf life (days): 365

CAS Number: 2170488-92-1

Notes: L202 is an ionizable cationic lipid (pKa = 6.04) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA.{51307} Intramuscular administration of LNPs containing L202 and encapsulating nucleoside-modified mRNA encoding pre-fusion stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, also known as surface glycoprotein, increase plasma levels of IgG antibodies targeting SARS-CoV-2 spike glycoprotein in mice and cynomolgus monkeys.

• Artikelnummer: CAY37841-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37841-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe