Anti-Rat CD4 Purified (Clone W3/25) (mouse IgG1)

Cedarlane’s anti-rat T helper cell monoclonal antibodiesrecognize a determinant on the majority of thymocytes (90-95%), a subset ofperipheral T cells and peritoneal macrophages (1,2,3,10). The antigenrecognized by this clone is a surface glycoprotein of Mr 48 000 - 52 000 and isthe homologue of the human CD4 and the mouse L3/T4 antigen. Clone W3/25 labelsthe rat T helper subset, which mediates the helper activity for B and T cells,graft vs. host (GVH) reactivity and produces IL-2 in the mixed lymphocyte reaction(MLR) (2,4,6). Addition of W3/25 to the MLR, inhibited proliferation and blocksthe production of IL-2 (4,5,6,9).

• Artikelnummer: CEDCL003AP
• Hersteller: Cedarlane
• Hersteller Artikelnummer: CL003AP
• Green Labware: Nein
• Verpackungseinheit: 250µg
• Mengeneinheit: STK
• Reaktivität: Rat (Rattus)
• Methode: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Flow Cytometry, Functional Assay
• Isotyp: IgG1
• Wirt: Mouse