Anti-Cancer Natural Product Library

Description: With features of enormous scaffold diversity and structural complexity, natural products (NPs) are the main sources of lead compounds and new drugs and play a highly significant role in the drug discovery and development process, especially for cancer and infectious diseases. A large number of natural products have been proven to have potential anti-tumor effects, mainly from plants, animals, Marine organisms and microorganisms. At present, derived than 60% of anti-tumor drugs come from natural sources, and they are widely used in breast, prostate and colon cancers.
With features of enormous scaffold diversity and structural complexity, natural products (NPs) are the main sources of lead compounds and new drugs and play a highly significant role in the drug discovery and development process, especially for cancer and infectious diseases. A large number of natural products have been proven to have potential anti-tumor effects, mainly from plants, animals, Marine organisms and microorganisms. At present, derived than 60% of anti-tumor drugs come from natural sources, and they are widely used in breast, prostate and colon cancers.
MCE offers a unique collection of 1582 natural products with validated anti-cancer activity. MCE anti-cancer natural product library is a useful tool for anti-tumor drugs screening and other related research.
MCE Anti-Cancer Natural Product Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 1534 compounds supplied in 10 mM solution, 35 compounds supplied in 2 mM solution and 13 compounds supplied in 3 mg/mL solution.
For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

Advantages:

• A unique collection of 1582 natural products with validated and potential anti-cancer activity for high throughput screening (HTS) and high content screening (HCS).
• A useful tool for the discovery of anti- cancer drugs.
• Target diverse, medicinally active and cell permeable.
• Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.
• More detailed compound information with structure, IC50, and other chemical & biological data.
• High purity and quality validated by NMR and LC/MS.

Formulation: A collection of 1582 natural products supplied as pre-dissolved Solutions or SolidSolution:1534 compounds supplied in 10 mM solution,35 compounds supplied in 2 mM solution,13 compounds supplied in 3 mg/mL solution.

Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty.384-well plate: the first two columns and the last two columns are left empty.Compounds with different concentrations or dissolved in different solvents will be put on separate plates.This way of layout may increase the number of plates because there could be three solvents and three concentrations. If you have other requirements, please let us know.

Container: 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

• Artikelnummer: MEXHY-L107-2x100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-L107-2x100
• Green Labware: Nein
• Verpackungseinheit: 2 x 100 μl
• Mengeneinheit: PAK