Exosomes Compound Library

Exosomes Compound Library
Artikelnummer
MEXHY-L072-250
Verpackungseinheit
250 μl
Hersteller
MedChemExpress

Verfügbarkeit: wird geladen...
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Description: Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.
Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.
The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 46 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.
MCE Exosomes Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 45 compounds supplied in 10 mM solution and 1 compounds supplied in 3 mg/mL solution.
For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

Advantages:
  • A unique collection of 46 exsomes secretion-related small molecules.
  • A useful tool for drug discovery of exsomes secretion-related diseases.
  • Bioactivity and safety confirmed by preclinical research and clinical trials. Some inhibitors have been approved by FDA.
  • Structurally diverse, medicinally active, and cell permeable.
  • More detailed compound information with structure, IC50, and brief introduction.
  • NMR and HPLC validated to ensure high purity and quality.
  • All compounds are in stock and continuously updated.


Formulation: A collection of 46 exosomes compounds supplied as pre-dissolved Solutions or SolidSolution:45 compounds supplied in 10 mM solution,1 compounds supplied in 3 mg/mL solution.

Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty.384-well plate: the first two columns and the last two columns are left empty.Compounds with different concentrations or dissolved in different solvents will be put on separate plates.This way of layout may increase the number of plates because there could be three solvents and three concentrations. If you have other requirements, please let us know.

Container: 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Mehr Informationen
Artikelnummer MEXHY-L072-250
Hersteller MedChemExpress
Hersteller Artikelnummer HY-L072-250
Green Labware Nein
Verpackungseinheit 250 μl
Mengeneinheit STK
Produktinformation (PDF)
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MSDS (PDF)
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