FAM FLICA CASPASE-1 KIT

FAM FLICA CASPASE-1 KIT
Artikelnummer
AVIOKSA11275
Verpackungseinheit
100 Tests
Hersteller
Aviva Systems Biology

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Conjugation: Carboxyfluorescein

Description of Target: The FAM FLICATM Capase 1 kit uses a target sequence (YVAD) sandwiched between a green fluorescent label, FAM, and FMK to make a quick and flexible method to analyze active capases in apoptotic cells. These kits measure apoptosis by detecting active caspases in whole, living cells. They don't work by using antibodies or an ELISA. Instead, their methodology is based a unique cell-permeable and non-cytotoxic reagent called Fluorochrome Inhibitor of Caspases. These kits are suitable for cells in suspension, adherent cells, thin tissue sections (but not fixed or paraffin-embedded cells) from many species including mammalian, insect, and yeast. Different cell types, e.g. HeLa, primary neurons, macrophages and lymphocytes have also been successfully studied with these kits.

Key Reference:
References:
1. Hoegen, T. et al. (2011) The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is
Activated through ATP-Dependent Lysosomal Cathepsin B Release. J Immunol. 187: 5440-51.

Product Format: Kit

Specificity#: CASPASE-1
Mehr Informationen
Artikelnummer AVIOKSA11275
Hersteller Aviva Systems Biology
Hersteller Artikelnummer OKSA11275-100T
Green Labware Nein
Verpackungseinheit 100 Tests
Mengeneinheit PAK
Reaktivität Human
Methode Immunofluorescence, Flow Cytometry
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