Fractin Antibody

Fractin Antibody
Artikelnummer
ROC100-401-D40
Verpackungseinheit
100 µL
Hersteller
Rockland

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Application Note: Anti-Fractin (Rabbit) Antibody has been tested by western blot, ICC, and IHC. Excepted reactivity to the 32 kDa fractin protein in Western blots. Specific conditions for reactivity should be optimized by the end user.

Concentration Value: Titrated value sufficient to run approximately 10 mini blots.

Immunohistochemistry Dilution: 1:100

Western Blot Dilution: 1:1000

General Disclaimer Note: This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.

Immunogen: Anti-Fractin Antibody was produced in rabbit by repeated immunizations with Fractin- Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

Physical State: Liquid

Purity and Specificity: Anti-Fractin antibody is directed against human Fractin. Anti-Fractin antibodies were prepared from monospecific neat serum. Anti-Fractin antibody is specific for the ~32 kDa fractin protein in Western blots with no reactivity to intact actin. There is often a ladder of smaller bands in cells or culture or in vivo preparations due to further degradation by other proteases. Reactivity is expected against human and rat.

Background: Fractin Antibody detects human Fractin (fragment of actin) which is a caspase-specific cleavage product of actin and serves as a novel marker of apoptosis-related events. The antibody has been shown to detect the processes and cell bodies of degenerating neurons and plaque-associated microglia in Alzheimer’s disease. It has recently been reported that Fractin may have a functional role in apoptotic signaling in oligodendrocytes. Anti-Fractin Antibody is ideal for investigators involved in Cell Apoptosis and, more generally in Neuroscience.

Low Endotoxin: No
Mehr Informationen
Artikelnummer ROC100-401-D40
Hersteller Rockland
Hersteller Artikelnummer 100-401-D40
Verpackungseinheit 100 µL
Mengeneinheit STK
Reaktivität Human, Rat (Rattus)
Klonalität Polyclonal
Methode Western Blotting, Immunohistochemistry
Isotyp Antiserum
Human Gene ID 60
Wirt Rabbit
Konjugat Unconjugated
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