Abbreviation: Galectin 3/LGALS3
Target Synonym: LGALS3;CBP35;GAL3;GALBP;GALIG;L31;LGALS2;MAC2
Conjugation: Unconjugated
UNIProt ID: P17931
Background: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human Galectin 3/LGALS3
Dilution: WB 1:500-1:2000,IHC 1:50-1:200,IF 1:50-1:200